PYXS

Pyxis Oncology price target lowered to $5 from $7 at H.C. Wainwright

H.C. Wainwright lowered the firm’s price target on Pyxis Oncology (PYXS) to $5 from $7 and keeps a Buy rating on the shares. Pyxis announced its decision to de-prioritize development of anti-Siglec-15 antibody PYX-106 to focus on PYX-201, its lead antibody-drug conjugate targeting Extra Domain B Splice Variant of Fibronectin, the analyst tells investors in a research note. The firm is not surprised by the decision since the potential of Siglec-15 is “questionable” given the lack of efficacy NC318, another Siglec-15-targeting antibody that has been discontinued, and thinks it’s prudent to de-prioritize PYX-106, which could help Pyxis better manage its operational expenses and focus on PYX-201 development.

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