Immuneering Corporation establishes a Pancreatic Cancer Advisory Board to enhance clinical guidance for its lead candidate, IMM-1-104.
Quiver AI Summary
Immuneering Corporation has established a Pancreatic Cancer Advisory Board, consisting of prominent oncology researchers, to provide strategic guidance on its lead clinical program, IMM-1-104, which is currently progressing through trials. This formation follows the recent Orphan Drug and Fast Track designations for IMM-1-104 in treating pancreatic cancer. The company's CEO, Ben Zeskind, expressed enthusiasm about the board's expertise in advancing treatment options for pancreatic cancer patients. IMM-1-104 is designed to selectively target cancer cells while minimizing effects on healthy cells, and the advisory board's insights will support its clinical development as Immuneering aims to enhance its therapeutic pipeline.
Potential Positives
- Establishment of the Pancreatic Cancer Advisory Board signifies strategic advancement in clinical development for IMM-1-104, reflecting the company's commitment to improving treatment options in pancreatic cancer.
- The advisory board consists of world-renowned oncology clinical researchers, which enhances the credibility and expertise guiding Immuneering's clinical programs.
- IMM-1-104 has recently received Orphan Drug designation and Fast Track designations from the FDA, indicating its potential significance in addressing unmet medical needs in pancreatic cancer.
- The ongoing Phase 1/2a study of IMM-1-104 aims to provide further clinical evidence of its efficacy in treating advanced solid tumors with RAS mutations, bolstering the company's therapeutic pipeline.
Potential Negatives
- The company has incurred significant losses and is not currently profitable, raising concerns about its financial sustainability and ability to continue operations.
- The lengthy and uncertain process of clinical drug development poses risks including potential delays in or failure to obtain necessary regulatory approvals.
- As a clinical-stage company relying on third-party collaborations, there is a risk of complications or failures in conducting clinical trials and manufacturing its product candidates.
FAQ
What is the purpose of the Pancreatic Cancer Advisory Board?
The board provides strategic medical and clinical guidance to advance Immuneering's clinical program IMM-1-104.
What designations has IMM-1-104 received?
IMM-1-104 has received Orphan Drug designation and Fast Track designations for pancreatic cancer treatments.
How does IMM-1-104 aim to treat cancer?
IMM-1-104 employs Deep Cyclic Inhibition of the MAPK pathway to selectively target cancer cells.
Where is IMM-1-104 currently being evaluated?
IMM-1-104 is undergoing a Phase 1/2a study for patients with advanced solid tumors harboring RAS mutations.
Who are the members of the Pancreatic Cancer Advisory Board?
The board includes prominent oncologists from institutions like Mayo Clinic and MD Anderson Cancer Center.
Disclaimer: This is an AI-generated summary of a press release distributed by GlobeNewswire. The model used to summarize this release may make mistakes. See the full release here.
$IMRX Hedge Fund Activity
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Full Release
- Establishment reflects the clinical progress of IMM-1-104 and its promise in pancreatic cancer -
- Follows recent Orphan Drug designation in pancreatic cancer and Fast Track designations in first- and second-line pancreatic cancer for IMM-1-104 -
CAMBRIDGE, Mass., Dec. 19, 2024 (GLOBE NEWSWIRE) -- Immuneering Corporation (Nasdaq: IMRX), a clinical-stage oncology company seeking to develop and commercialize universal-RAS/RAF medicines for broad populations of cancer patients, today announced the formation of its Pancreatic Cancer Advisory Board. The advisory board, which comprises world-renowned oncology clinical researchers, will provide strategic medical and clinical guidance to the company as its pipeline, including lead clinical program IMM-1-104, continues to advance.
“We are delighted to welcome such an accomplished group of oncologists with significant clinical research expertise to our newly established pancreatic cancer advisory board,” said Ben Zeskind, Ph.D., Co-Founder and CEO of Immuneering. “Each member brings extensive oncology experience and knowledge of the patient journey that will be invaluable as we continue to advance IMM-1-104 further into clinical development. The formation of this board reflects the progress we are making in our efforts to develop better options for pancreatic cancer patients.”
The Company’s Pancreatic Cancer Advisory Board includes the following members:
Tanios Bekaii-Saab, M.D.
, Professor of Medicine, Mayo Clinic
Vincent Chung, M.D., FACP
, Professor of Medical Oncology and Therapeutics Research, City of Hope
Shubham Pant, M.D.
, Professor, GI Medical Oncology, MD Anderson Cancer Center
Jordan Berlin, M.D., FASCO
, Professor of Medicine, Director, Division of Hematology and Oncology, Department of Medicine, Vanderbilt-Ingram Cancer Center
See Immuneering’s
website
for additional information on the advisory board.
About IMM-1-104
IMM-1-104 aims to achieve universal-RAS activity that selectively impacts cancer cells to a greater extent than healthy cells, through Deep Cyclic Inhibition of the MAPK pathway with once-daily dosing. IMM-1-104 is currently being evaluated in a Phase 1/2a study in patients with advanced solid tumors harboring RAS mutations (NCT05585320).
About Immuneering Corporation
Immuneering is a clinical-stage oncology company seeking to develop and commercialize universal-RAS/RAF medicines for broad populations of cancer patients with an initial aim to develop a universal-RAS therapy. The Company aims to achieve universal activity through Deep Cyclic Inhibition of the MAPK pathway, impacting cancer cells while sparing healthy cells. Immuneering’s lead product candidate, IMM-1-104, is an oral, once-daily Deep Cyclic Inhibitor currently in a Phase 2a trial in patients with advanced solid tumors including those harboring RAS mutations. IMM-6-415 is an oral, twice-daily Deep Cyclic Inhibitor currently in a Phase 1/2a trial in patients with advanced solid tumors harboring RAS or RAF mutations. The company’s development pipeline also includes several early-stage programs. For more information, please visit
www.immuneering.com
.
Forward-Looking Statements
This press release contains forward-looking statements, including within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release that do not relate to matters of historical fact should be considered forward-looking statements, including, without limitation, statements regarding: Immuneering’s plans to develop, manufacture and commercialize its product candidates; the treatment potential and promise of IMM-1-104 and IMM-6-415, alone or in combination with other agents, including chemotherapy and pancreatic cancer; the clinical progress of IMM-1-104 and the ability of the advisory board to help advance the company’s programs; and the timing for release of additional results from the Phase 2a portion of the trial for IMM-1-104 and the Phase 1 portion of the trial for IMM-6-415.
These forward-looking statements are based on management’s current expectations. These statements are neither promises nor guarantees, but involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements, including, but not limited to, the following: the risks inherent in oncology drug research and development, including target discovery, target validation, lead compound identification, and lead compound optimization; we have incurred significant losses, are not currently profitable and may never become profitable; our projected cash runway; our need for additional funding and ability to continue as a going concern; our unproven approach to therapeutic intervention; our ability to address regulatory questions and the uncertainties relating to regulatory filings, reviews and approvals; the lengthy, expensive, and uncertain process of clinical drug development, including potential delays in or failure to obtain regulatory approvals; our reliance on third parties and collaborators to conduct our clinical trials, manufacture our product candidates, and develop and commercialize our product candidates, if approved; failure to compete successfully against other drug companies; protection of our proprietary technology and the confidentiality of our trade secrets; potential lawsuits for, or claims of, infringement of third-party intellectual property or challenges to the ownership of our intellectual property; our patents being found invalid or unenforceable; costs and resources of operating as a public company; and unfavorable or no analyst research or reports.
These and other important factors discussed under the caption “Risk Factors” in our Quarterly Report on Form 10-Q for period ended September 30, 2024, and our other reports filed with the U.S. Securities and Exchange Commission, could cause actual results to differ materially from those indicated by the forward-looking statements made in this press release. Any such forward-looking statements represent management's estimates as of the date of this press release. While we may elect to update such forward-looking statements at some point in the future, except as required by law, we disclaim any obligation to do so, even if subsequent events cause our views to change. These forward-looking statements should not be relied upon as representing our views as of any date subsequent to the date of this press release.
Media Contact:
Gina Nugent
gina@nugentcommunications.com
Investor Contact:
Laurence Watts
619-916-7620
laurence@newstreetir.com
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