AXSM

Axsome AXS-05 results in ADA ‘positive,’ drug looks ‘approvable,’ says Truist

After Axsome Therapeutics (AXSM) reported topline data from the studies of AXS-05 in Alzheimer’s disease agitation, Truist analyst Joon Lee noted that while the ADVANCE-2 study missed statistical significance, “more importantly,” ACCORD-2 was statistically significantly positive on both the primary and key secondary endpoints, making it the third positive study of AXS-05 in ADA. The firm, which currently models risk-unadjusted sales of AXS-05 in ADA of $2.3B in 2034, argues that the ADA results are “highly positive” and views AXS-05 as approvable for ADA. The firm, which adds that its model is under review, has a Buy rating and $150 price target on Axsome shares, which are down $7.02, or 8%, to $79.68 in early Monday trading.

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