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Advanced Micro Devices vs. ASML: Which Semiconductor Stock Is a Better Buy in 2026?

Key Points

  • Advanced Micro Devices is rapidly expanding its presence in the AI data center market through strategic partnerships and high-performance GPU releases.

  • ASML maintains a near-monopoly on the lithography equipment essential for producing the world's most advanced microchips.

  • Which semiconductor stock deserves a spot in your portfolio?

  • 10 stocks we like better than Advanced Micro Devices ›

The semiconductor landscape is shifting as artificial intelligence requires more powerful hardware. Choosing between Advanced Micro Devices (NASDAQ:AMD) and ASML (NASDAQ:ASML) means deciding between a chip designer and the equipment maker powering the entire industry.

AMD designs the processors and graphics units used in data centers. Meanwhile, ASML builds the complex lithography machines used to print circuits on silicon. Investors often use the P/S ratio, which compares market value to sales over the past twelve months, to evaluate these businesses.

The case for Advanced Micro Devices

AMD focuses on high-performance computing, selling CPUs and GPUs to data centers and gaming brands. Its latest annual report, filed in early 2025, highlights a multiyear partnership with OpenAI for artificial intelligence infrastructure. The company also supplies chips for consoles made by Sony and Microsoft (NASDAQ:MSFT). AMD relies on a small number of customers for a substantial portion of its revenue, including hyperscale data center operators. Customer concentration like this adds a layer of risk to the business.

In FY 2025, revenue reached nearly $34.6 billion, representing a significant 34.3% increase. This growth helped the company generate a net income of approximately $4.3 billion, representing a net margin of roughly 12.5%. The expansion was driven by demand for data center products among semiconductor stocks. This trajectory follows a consistent upward trend, showing the company's ability to capture market share.

As of its December 2025 balance sheet, the current ratio is roughly 2.9x, measuring the ability to pay short-term obligations. The debt-to-equity ratio is approximately 0.1x, a metric comparing total debt to shareholder equity. Free cash flow was nearly $6.7 billion, defined as cash from operations minus capital expenditures. Note that stock-based compensation represented roughly 21.2% of operating cash flow, which inflates reported cash generation since SBC is a non-cash expense.

The case for ASML

ASML is the sole provider of extreme ultraviolet lithography machines, which are required to manufacture the most advanced chips in the world. It serves the global semiconductor ecosystem with operations across Europe, North America, and Asia. Major customers are not explicitly disclosed in its latest annual report, filed in early 2025, but the company's tools are used by every major leading-edge foundry. Its business model relies on selling these multi-million dollar machines and providing long-term service and software support to chipmakers.

For FY 2025, the company reported revenue of close to $36.6 billion, a 15.6% increase compared to the prior year. Net income reached approximately $10.8 billion, resulting in a net margin of 29.4%. The net margin shows the percentage of revenue remaining as profit after all expenses are paid. This performance reflects steady demand as foundries expand capacity to meet global chip needs.

Based on its December 2025 balance sheet, the debt-to-equity ratio is roughly 0.1x, showing a conservative use of borrowed money relative to equity. The current ratio is approximately 1.3x, indicating the company has more than enough assets to cover its upcoming bills. Free cash flow for the fiscal year was nearly $12.4 billion, which is the cash left over after paying for operations and capital equipment.

Risk profile comparison

AMD faces intense competition in its primary markets, particularly from Intel (NASDAQ:INTC) in processors and Nvidia (NASDAQ:NVDA) in graphics chips. The company relies heavily on third-party manufacturers, primarily Taiwan Semiconductor Manufacturing Company (NYSE:TSM), meaning any supply chain disruptions could materially harm its operations. Furthermore, AMD is subject to significant geopolitical risks and stringent export control regulations regarding sales to China. These rules limit its ability to export advanced AI and semiconductor products to certain regions.

ASML operates in a highly specialized field, but it still faces risks from the cyclical nature of the chip industry. Geopolitical tensions are a major concern, as governments may restrict the export of its most advanced lithography systems to certain countries. Additionally, the company must continuously invest in research and development to maintain its technological lead. Any delays in developing the next generation of machines could allow competitors to gain ground or cause customers to postpone their capital spending plans.

Valuation comparison

ASML appears more conservatively valued based on its Forward P/E, which uses future earnings estimates, while AMD carries a higher premium.

MetricAdvanced Micro DevicesASML
Forward P/E84.5x41.6x
P/S ratio25.5x17.6x

Valuation metrics include sourcing from Financial Modeling Prep (FMP) and may differ from other data providers.

Which stock would I buy in 2026?

I'd go with ASML. Its position in the semiconductor industry is unlike almost anything else in the market. Every major AI chip, designed by companies like Nvidia, AMD, and Apple, is manufactured using ASML's machines. There is no credible alternative at the cutting edge, and AI demand is driving demand higher. Its most recent quarter beat estimates, the full-year outlook was raised substantially, and AI-driven demand from chip manufacturers continues to accelerate.

AMD deserves credit for its own strong run. Data center sales have more than doubled year over year and its partnership with Anthropic points to sustained demand beyond the current quarter. And with six consecutive quarters of above 30% growth, it's got a track record worth respecting. For investors who want direct exposure to the AI chip market, it is a strong choice.

But AMD competes in a market where Nvidia holds an enormous lead. ASML is my pick because it serves everyone in that race, including AMD itself. For a patient investor, owning the company that the entire AI chip industry depends on is simply a more durable long-term position.

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Sara Appino has positions in Apple, Nvidia, and Taiwan Semiconductor Manufacturing. The Motley Fool has positions in and recommends ASML, Advanced Micro Devices, Apple, Intel, Microsoft, Nvidia, and Taiwan Semiconductor Manufacturing. The Motley Fool has a disclosure policy.

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